Propionate oxaloacetate

Lipids and amino acids can also be used as energy sources, but they enter the main pathways at different points. C. elegans has a functional methylmalonyl-CoA epimerase (racemase) that is involved in propionyl-CoA metabolism for the degradation of branched amino acids and odd-chain fatty acids ( Kühnl et al., 2005 ). Fatty acid moieties of lipids are broken down by β -oxidation into acetyl-CoA (which in turn can enter the TCA cycle). β -oxidation occurs in the mitochondrial matrix and also yields reduced electron carriers. Peroxisomal β -oxidation of long-chain fatty acids is not linked directly to energy metabolism because the reduced electron carrier is directly oxidized by molecular oxygen (yielding hydrogen peroxide). Amino acids can be broken down via distinct pathways and their carbon skeletons can be metabolized in the TCA cycle.

Propionate oxaloacetate

propionate oxaloacetate

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