As a C17-aa anabolic steroid, Winstrol is hepatotoxic and will present stress to the liver. A common misconception many make is assuming only the oral version of this steroid is hepatotoxic. Winstrol can be found as an oral tablet or as an injectable solution but both forms are C17-aa and both stressful to the liver. In fact, injectable Winstrol is one of the only C17-aa injectable steroids. Many also inaccurately assume this is one of the most hepatotoxic anabolic steroids on the market; again this is false. Stanozolol will carry a greater hepatotoxicity than steroids like Anavar (Oxandrolone) but on a per milligram basis less hepatotoxic than steroids like Dianabol (Methandrostenolone).
For women, things are a bit different. They do not need SERMs because they produce so little testosterone naturally that suppression isn’t as detrimental. However, Anavar and Winstrol act much like testosterone in the female body, and using the combination over the course of four to six weeks can create a hormonal imbalance. Women who simply come off steroids cold turkey, even after a few weeks, may notice undesirable effects like fatigue and irritability. To avoid this, simply reducing dose toward the end of the cycle can help tremendously.